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Less than a week into my own self-isolation, my Brooklyn apartment—which had previously given me such pleasure—began to feel like a prison. Suddenly, I was under house arrest and the Quarantine Toilet Paper Class Of 2020 Graduation Senior Shirt also I will do this sentence was indefinite. I was safe, sure, but I was also deeply, profoundly alone. My mind started reeling: Am I really not going to see my family or friends for over a year? Will I ever see them again I began to feel symptomatic. My throat felt tight and scratchy. I couldn’t breathe. Was I sick? As it turned out, I was not experiencing symptoms of coronavirus; my panicked downward spiral was, according to social neuroscientist Dr. Stephanie Cacioppo, a natural stress response triggered by my brain.

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“Less than a week into my own self-isolation, my Brooklyn apartment—which had previously given me such pleasure—began to feel like a prison. The worst thing that we can do as humans is to imagine a future where we are alone,” she told me over the Quarantine Toilet Paper Class Of 2020 Graduation Senior Shirt also I will do this phone. Dr. Cacioppo, the director of the Brain Dynamics Laboratory at the University of Chicago’s Pritzker School of Medicine, studies the effects of love and loneliness in the brain. She, along with her late husband Dr. John Cacioppo (who literally wrote the book on loneliness), has found that the physical state of being alone actually has very little to do with feeling lonely. Their research likens loneliness to a biological signal, much like thirst or hunger.